Circadian sleep/wake cycle |
Locomotor activity in diurnal cycle: light phase |
Increased |
Home cage behavior |
Adult |
Hisaoka T , et al. (2018)
|
Circadian sleep/wake cycle |
Adaptation to dark phase |
No change |
Home cage behavior |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
Self grooming: home cage/familiar environment |
No change |
Home cage behavior |
Adult; 1-2 months |
Hisaoka T , et al. (2018)
|
Motor phenotype |
Motor learning |
Increased |
Accelerating rotarod test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
Motor coordination and balance |
No change |
Accelerating rotarod test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
General locomotor activity: ambulatory activity |
Increased |
Open field test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
General locomotor activity: ambulatory activity |
Increased |
Light-dark exploration test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
General locomotor activity: ambulatory activity |
No change |
Three-chamber social approach test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
General locomotor activity |
Increased |
Light-dark exploration test |
Adult |
Hisaoka T , et al. (2018)
|
Motor phenotype |
General locomotor activity |
Increased |
Elevated plus maze test |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Olfactory bulb morphology |
No change |
Histology |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Hippocampal morphology |
No change |
Histology |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Cerebellar morphology |
No change |
Histology |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Brain size |
No change |
Gross necroscopy |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Brain morphology |
No change |
Histology |
Adult |
Hisaoka T , et al. (2018)
|
Neuroanatomy / Ultrastructure / Cytoarchitecture |
Brain morphology |
No change |
Gross necroscopy |
Adult |
Hisaoka T , et al. (2018)
|
Neurophysiology |
NA |
Not reported |
NA |
NA |
Hisaoka T , et al. (2018)
|
Repetitive behavior |
Repetitive digging |
No change |
Home cage behavior |
Adult |
Hisaoka T , et al. (2018)
|
Seizure |
NA |
Not reported |
NA |
NA |
Hisaoka T , et al. (2018)
|
Sensory |
Visual placing reflex |
No change |
Visual placing test |
Adult |
Hisaoka T , et al. (2018)
|
Sensory |
Startle response: acoustic stimulus |
Increased |
Acoustic startle reflex test |
Adult |
Hisaoka T , et al. (2018)
|
Sensory |
Sensorimotor gating |
No change |
Prepulse inhibition |
Adult |
Hisaoka T , et al. (2018)
|
Sensory |
Pain or nociception |
Decreased |
Foot shock test |
Adult |
Hisaoka T , et al. (2018)
|
Sensory |
Olfaction |
No change |
Buried food test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social memory |
Decreased |
Olfactory habituation-dishabituation test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social memory |
Decreased |
Habituation-dishabituation test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social memory |
Decreased |
Three-chamber social approach test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social habituation |
No change |
Habituation-dishabituation test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social dominance |
Decreased |
Resident-intruder test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social dishabituation |
Decreased |
Habituation-dishabituation test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Social approach |
No change |
Three-chamber social approach test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Rearing behavior |
Increased |
Open field test |
Adult |
Hisaoka T , et al. (2018)
|
Social behavior |
Aggression |
Decreased |
Resident-intruder test |
Adult |
Hisaoka T , et al. (2018)
|
Physiological parameters |
NA |
Not reported |
NA |
NA |
Hisaoka T , et al. (2018)
|
Communications |
Ultrasonic vocalization: isolation induced |
Increased |
Monitoring ultrasonic vocalizations |
P3, p7, 2 weeks |
Hisaoka T , et al. (2018)
|
Communications |
Ultrasonic vocalization: interaction induced: opposite sex stimulus |
Decreased |
Monitoring ultrasonic vocalizations |
Adult |
Hisaoka T , et al. (2018)
|
Developmental profile |
Size/growth |
No change |
Body weight measurement |
1week-4months |
Hisaoka T , et al. (2018)
|
Emotion |
Exploratory activity: habituation |
No change |
Olfactory discrimination test |
Adult |
Hisaoka T , et al. (2018)
|
Emotion |
Anxiety |
No change |
Light-dark exploration test |
Adult |
Hisaoka T , et al. (2018)
|
Emotion |
Anxiety |
No change |
Elevated plus maze test |
Adult |
Hisaoka T , et al. (2018)
|
Emotion |
Anxiety |
Increased |
Open field test |
Adult |
Hisaoka T , et al. (2018)
|
Immune response |
NA |
Not reported |
NA |
NA |
Hisaoka T , et al. (2018)
|
Learning & memory |
Spatial working memory |
No change |
Morris water maze test |
Adult |
Hisaoka T , et al. (2018)
|
Learning & memory |
Olfactory learning and memory |
No change |
Olfactory habituation-dishabituation test |
Adult |
Hisaoka T , et al. (2018)
|
Learning & memory |
Cued or contextual fear conditioning: passive avoidance |
No change |
Passive avoidance test |
Adult |
Hisaoka T , et al. (2018)
|
Learning & memory |
Cognitive flexibility |
No change |
Morris water maze test |
Adult |
Hisaoka T , et al. (2018)
|
Maternal behavior |
NA |
Not reported |
NA |
NA |
Hisaoka T , et al. (2018)
|
Molecular profile |
Targeted expression |
Decreased |
Western blot |
Adult |
Hisaoka T , et al. (2018)
|