Genetic Animal Models 252 Genetic animal models

Database updated on June 22, 2017

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Status Gene Symbol Gene Name Model Species Number of Models Syntenic Human gene score Human Syndromic Rescue Model
SLC6A3solute carrier family 6 member 3Mus musculus14No30Yes
SLC6A3solute carrier family 6 member 3Rattus norvegicus4No30Yes
NTNG1Netrin G1Mus musculus1Unknown41No
ATRNL1Attractin-like 1Mus musculus3Unknown50No
DMPKdystrophia myotonica-protein kinaseMus musculus2UnknownS1No
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1Mus musculus7No30Yes
HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1Rattus norvegicus4NoS1Yes
PTENPhospatase and Tensin homologMus musculus20Unknown11Yes
HMGN1High mobility group nucleosome binding domain 1Mus musculus2Unknown30No
TCF4transcription factor 4Mus musculus3NoS1Yes
TCF4transcription factor 4Rattus norvegicus4NoS1Yes
GAP43growth associated protein 43Mus musculus1Unknown50No
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1Mus musculus3Yes40No
GRM8glutamate receptor, metabotropic 8Mus musculus1Unknown60No
NF1neurofibromin 1Mus musculus9UnknownS1Yes
GTF2Igeneral transcription factor IiiMus musculus2Unknown40No
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 2Mus musculus1Unknown30No
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3Mus musculus1No41No
WDFY3WD repeat and FYVE domain containing 3Mus musculus4Unknown20No
GADD45Bgrowth arrest and DNA-damage-inducible, betaMus musculus1No50No
GADD45Bgrowth arrest and DNA-damage-inducible, betaRattus norvegicus1No50No
DEAF1DEAF1, transcription factorMus musculus9Yes21No
IL1RAPL1interleukin 1 receptor accessory protein-like 1Mus musculus2Unknown40No
PARK2Parkinson disease (autosomal recessive, juvenile) 2, parkinMus musculus1Unknown30No
TSC2tuberous sclerosis 2Mus musculus15UnknownS1Yes
TSC2tuberous sclerosis 2Rattus norvegicus3UnknownS1Yes
GRID2glutamate receptor, ionotropic, delta 2Mus musculus2No40No
MECP2methyl-CpG binding protein 2Mus musculus62Unknown21Yes
MECP2methyl-CpG binding protein 2Rattus norvegicus1Unknown21No
OPRM1opioid receptor, mu 1Mus musculus3Yes50Yes
APBA2amyloid beta (A4) precursor protein-binding, family A, member 2Mus musculus2Unknown40No
CADPS2Ca2+-dependent activator protein for secretion 2Mus musculus5Yes40No
ATP1A3Sodium potassium ATPase alpha 3 subunitMus musculus2UnknownS1Yes
OXTROxytocin receptorMus musculus13Unknown30Yes
CTNNB1catenin (cadherin associated protein), beta 1Mus musculus1Yes30No
OPHN1Oligophrenin 1Mus musculus1Unknown30No
CXCR3chemokine (C-X-C motif) receptor 3Mus musculus1Unknown50No
RAI1retinoic acid induced 1Mus musculus2UnknownS1No
HOMER1homer scaffolding protein 1Mus musculus4No40No
HOMER1homer scaffolding protein 1Rattus norvegicus2No40No
FOLH1folate hydrolase (prostate-specific membrane antigen) 1Mus musculus3Yes50Yes
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Mus musculus2Unknown30No
NLGN4Xneuroligin 4, X-linkedMus musculus3Unknown30No
PRICKLE2prickle homolog 2 (Drosophila)Mus musculus2No30No
TPH2Tryptophan hydroxylase 2Mus musculus3No60No
NRP2neuropilin 2Mus musculus4Unknown40No
ANK2ankyrin 2, neuronalMus musculus2No10No
SCN1Asodium channel, voltage-gated, type I, alpha subunitMus musculus18UnknownS1Yes
SCN1Asodium channel, voltage-gated, type I, alpha subunitRattus norvegicus2UnknownS1Yes
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2Mus musculus8NoS1Yes
IMMP2LIMP2 inner mitochondrial membrane peptidase-likeMus musculus2Unknown50No
DAB1Disabled homolog 1Mus musculus1Unknown50No
DAB1Disabled homolog 1Rattus norvegicus1Unknown50No
SLC25A12solute carrier family 25 (Mitochondrial carrier, Aralar), member 12Mus musculus4Unknown40No
CLSTN3calsyntenin 3Mus musculus1No50No
RELNReelinMus musculus9Unknown10Yes
DYRK1Adual specificity tyrosine-Y- phosphorylation regulated kinase 1AMus musculus3No11No
EXT1exostosin 1Mus musculus1No40No
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1Mus musculus2No50No
NRXN2Neurexin2Mus musculus3No40No
NRXN1Neurexin 1Mus musculus2Unknown20No
NRXN1Neurexin 1Rattus norvegicus2Unknown20Yes
ALDH5A1Aldehyde Dehydrogenase 5 family, member A1Mus musculus4UnknownS1Yes
FOXP2Forkhead box P2Mus musculus9Unknown30No
FOXP1Forkhead box P1Mus musculus5Unknown20No
ADNPActivity-dependent neuroprotector homeoboxMus musculus7No11Yes
TBR1T-box, brain 1Mus musculus9No10Yes
CNTN4contactin 4Mus musculus1Unknown20No
ADORA2AAdenosine A2a receptorMus musculus2Unknown40No
DISC1Disrupted in schizophrenia 1Mus musculus11Unknown30No
DISC1Disrupted in schizophrenia 1Rattus norvegicus2Unknown30No
EN2Engrailed homeobox 2Mus musculus5Unknown40No
OXToxytocin/neurophysin I prepropeptide [Homo sapiens (human)Mus musculus7Yes40Yes
EIF4EEukaryotic translation initiation factor 4EMus musculus2Yes40Yes
SEMA5ASema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5AMus musculus1Unknown30No
BCKDKbranched chain ketoacid dehydrogenase kinaseMus musculus3No20Yes
BCKDKbranched chain ketoacid dehydrogenase kinaseRattus norvegicus1No20No
MEF2CMyocyte Enhancer Factor 2CMus musculus6Unknown41No
PCDH10protocadherin 10Mus musculus3Unknown40Yes
HDAC3Histone deacetylase 3Mus musculus1Yes50No
HDAC4Histone deacetylase 4Mus musculus2UnknownS1No
AHI1Abelson helper integration site 1Mus musculus3UnknownS1No
CDKL5cyclin-dependent kinase-like 5Mus musculus2NoS1No
CADM1cell adhesion molecule 1Mus musculus4Unknown40No
NLGN3neuroligin 3Mus musculus17Yes20Yes
NLGN3neuroligin 3Rattus norvegicus1Yes20No
NLGN1neuroligin 1Mus musculus3Unknown40No
PRKDCProtein kinase, DNA activated, catalytic peptideMus musculus2No40Yes
GRIK2glutamate receptor, ionotropic, kainate 2Mus musculus1No30No
GRIK4Glutamate receptor, ionotropic, kainate 4Mus musculus8No50Yes
VLDLRvery low density lipoprotein receptorRattus norvegicus1Unknown50No
HOXA1Homeobox A1Mus musculus3UnknownS1No
CRHR2Corticotropin releasing hormone receptor2Mus musculus2No50No
SLC4A10Solute carrier 4, sodium bicarbonate transporter, member 10Mus musculus1Unknown40No
SRRM4Serine/arginine repetitive matrix 4Mus musculus2Yes50No
PITX1paired-like homeodomain 1Mus musculus1Unknown40No
SCN2Asodium channel, voltage-gated, type II, alpha subunitMus musculus3Unknown10No
PRKCBProtein Kinase C, betaMus musculus1Unknown30No
SYNGAP1synaptic Ras GTPase activating protein 1Mus musculus9Unknown11No
ARHGAP33Rho GTPase activating protein 33Mus musculus6No50Yes
PTCHD1Patched domain containing 1Mus musculus5No20Yes
SLC6A4solute carrier family 6 member 4Mus musculus8Unknown40Yes
SLC6A4solute carrier family 6 member 4Rattus norvegicus3No40No
SLC6A8Solute carrier family 6 member 8Mus musculus2Yes40No
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4Mus musculus1Unknown40No
CAPRIN1RNA granule protein 105 (Caprin 1)Mus musculus2Unknown30No
PLNPhospholambanMus musculus1Unknown40No
CACNA1Hcalcium channel, voltage-dependent, T type, alpha 1H subunitMus musculus1Unknown20No
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunitMus musculus6UnknownS1No
CACNA1FCalcium channel, voltage-dependent, L type, alpha 1F subunitMus musculus1No40No
CACNA1GCav3.1 T-type Ca2+ ChannelMus musculus6Unknown40No
CUL3cullin 3Mus musculus4No10No
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)Mus musculus2Unknown50No
PER1Period homolog 1Mus musculus1Unknown40No
MAGEL2MAGE like 2Mus musculus1No21No
DMDDystrophinMus musculus6UnknownS1No
CC2D1ACoiled-coil and C2 domain containing 1AMus musculus5No30No
IFNGR1Interferon gamma receptor 1Mus musculus1No50No
SLC9A6solute carrier family 9, subfamily AMus musculus3NoS1No
UBA6ubiquitin-like modifier activating enzyme 6Mus musculus1No50No
RBFOX1RNA binding protein, fox-1 homologMus musculus2Unknown30No
ERBINerbb2 interacting proteinMus musculus2No20No
PAX6paired box 6Rattus norvegicus2NoS1Yes
EIF4EBP2eukaryotic translation initiation factor 4E binding protein 2Mus musculus5No50Yes
SYN3Syanpsin IIIMus musculus1No50No
SYN1Synapsin IMus musculus1No40No
PGLYRP2peptidoglycan recognition protein 2Mus musculus1No50No
TBX1T-box1Mus musculus1Unknown40No
CTNND2Catenin(cadherin associated protein), delta 2Mus musculus1Yes20No
STAT1Signal transducer and activator of transcription 1Mus musculus2No50No
GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 3Mus musculus17Unknown20Yes
GSTM1Glutathione S-transferase mu 1Mus musculus1Unknown40No
FMR1Fragile X Mental Retardation 1Mus musculus36UnknownS1Yes
FMR1Fragile X Mental Retardation 1Rattus norvegicus1UnknownS1No
UCN3Urocortin 3Mus musculus2No50No
ANKRD11ankyrin repeat domain 11Mus musculus3Unknown21No
PRICKLE1prickle homolog 1 (Drosophila)Mus musculus5No30No
ATG7Autophagy related 7Mus musculus2No50Yes
NRG1neuregulin 1Mus musculus1No50No
TERTTelomerase reverse transcriptaseMus musculus2No50Yes
DPP6dipeptidyl- petidase 6Mus musculus1No40No
POU3F2POU class 3 homeobox 2Mus musculus2No50No
KMT2ALysine methyltransferase 2AMus musculus3No21No
ESRRBEstrogen-related receptor betaMus musculus2Unknown40No
STK39Serine threonine Kinase 39 (STE20/SPS1 homolog, yeast)Mus musculus1Unknown40No
ARXaristaless related homeoboxMus musculus4UnknownS1No
DRD3Dopamine receptor D3Mus musculus3Unknown40No
HTR1B5-hydroxytryptamine (serotonin) receptor 1BMus musculus2Unknown40No
NRCAMNeural cell adhesion moleculeMus musculus1Unknown40No
DHCR77-dehydrocholesterol reductaseMus musculus5NoS1No
CSNK1Dcasein kinase 1, deltaMus musculus3No60No
DVL1Dishevelled segment polarity protein 1Mus musculus8No50Yes
BRINP1BMP/RA-inducible neural-specific protein 1Mus musculus3Unknown50Yes
CACNA2D3calcium voltage-gated channel auxiliary subunit alpha2delta 3Mus musculus2Yes20No
ATP2B2TPase, Ca++ transporting, plasma membrane 2Mus musculus1No30No
Slc30a3Solute carrier family 30 (zinc transporter), member 3Mus musculus2Yes50Yes
SLC7A5solute carrier family 7 member 5Mus musculus2No30Yes
CHD7chromodomain helicase DNA binding protein 7Mus musculus4NoS1Yes
UBE3Bubiquitin protein ligase E3BMus musculus1No50No
CHD8chromodomain helicase DNA binding protein 8Mus musculus10No11Yes
UBE3Aubiquitin protein ligase E3AMus musculus21Unknown31Yes
NBEAneurobeachinMus musculus2Unknown40No
HTR2A5-hydroxytryptamine (serotonin) receptor 2AMus musculus4Unknown50No
IFNGInterferon gammaMus musculus3No50Yes
TSC1Tuberous sclerosis 1Mus musculus17UnknownS1Yes
APCadenomatous polyposis coliMus musculus2No50No
AVParginine vasopressinRattus norvegicus6No50Yes
TRPC6Transient receptor potential cation channel, subfamily C, member 6Mus musculus4No30Yes
BAIAP2BAI1-associated protein 2Mus musculus4Unknown50Yes
MCPH1microcephalin 1Mus musculus2Unknown40No
EPHA6EPH Receptor A6Mus musculus1Unknown50No
JAKMIP1janus kinase and microtubule interacting protein 1Mus musculus1Yes50No
GAD1glutamate decarboxylase 1 (brain, 67kDa)Mus musculus1No50No
MAPK1mitogen-activated protein kinase 1Mus musculus1Unknown50No
ASH1LASH1 like histone lysine methyltransferaseMus musculus4No10Yes
ATP8A1Aminophospholipid translocase, filppase, 8a1Mus musculus2Yes50No
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2Mus musculus1Yes50No
METmet Proto-oncogeneMus musculus8Unknown20No
WWOXWW domain containing oxidoreductaseRattus norvegicus1No30No
FOXG1Forkhead Box G1Mus musculus1Unknown50No
BCL11AB-cell CLL/lymphoma 11AMus musculus1Yes21No
SLC33A1Solute carrier family 33 member 1Mus musculus2Unknown50Yes
CNTNAP2contactin associated protein-like 2Mus musculus24Unknown21Yes
CNTNAP2contactin associated protein-like 2Rattus norvegicus1Unknown21No
CNTNAP4contactin associated protein-like 4Mus musculus7No30Yes
DSCAMDown syndrome cell adhesion moleculeMus musculus2No10No
P2RX4purinergic receptor P2X, ligand-gated ion channel, 4Mus musculus2No50No
FEZF2FEZ family zinc finger 2Mus musculus1Unknown40No
ARHGAP32Rho GTPase activating protein 32Mus musculus3No40Yes
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2Mus musculus2No40No
TSHZ3Teashirt zinc finger homeobox 3Mus musculus2No40No
NR3C2nuclear receptor subfamily 3, group C, member 2Mus musculus2Unknown30No
SHANK3SH3 and multiple ankyrin repeat domains 3Mus musculus35Unknown11Yes
SHANK3SH3 and multiple ankyrin repeat domains 3Rattus norvegicus4Unknown11Yes
SHANK2SH3 and multiple ankyrin repeat domains 2Mus musculus14No20Yes
SHANK1SH3 and multiple ankyrin repeat domains 1Mus musculus2Unknown30No
PVALBParvalbuminMus musculus3No50No
GRIN2BGlutamate receptor, ionotropic, N-methyl D-aspartate 2BMus musculus10No10No
AUTS2Autism susceptibility candidate 2Mus musculus2No30No
AVPR1AArginine vasopressin receptor 1AMus musculus2Unknown30No
CHD2chromodomain helicase DNA binding protein 2Mus musculus2No21No
DVL3Dishevelled segment polarity protein 3Mus musculus5No40Yes
GABRA5Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5Mus musculus1Yes50No
GLRA2glycine receptor, alpha 2Mus musculus1Unknown50No
GRIP1Glutamate receptor interacting protein 1Mus musculus2Unknown20No
GRPRgastrin-releasing peptide receptorMus musculus5Unknown50No
GSK3Bglycogen synthase kinase 3 betaMus musculus1Unknown50No
HDChistidine decarboxylaseMus musculus10No50Yes
HTR3A5-hydroxytryptamine (serotonin) receptor 3AMus musculus3Unknown40No
MAOAMonoamine Oxidase AMus musculus3Unknown40No
MBD3methyl-CpG binding domain protein 3Mus musculus1Unknown40No
NPAS2neuronal PAS domain protein 2Mus musculus1Unknown40No
TOP3BTopoisomerase (DNA) 3 BetaMus musculus2No40No
SLITRK5SLIT and NTRK-like family, member 5Mus musculus2No0No
CELF6CUGBP, Elav-like family member 6Mus musculus1No0No
CELF4CUGBP, Elav-like family member 4Mus musculus7No0No
GRM5glutamate receptor, metabotropic 5Mus musculus12No0No
DLG4discs, large homolog 4 (Drosophila)Mus musculus1Unknown0No
GRID1glutamate receptor, ionotropic, delta 1Mus musculus1No0No
LRRC7Leucine rich repeat containing 7Mus musculus1Unknown0No
SCN8Asodium channel, voltage gated, type VIII, alpha subunitMus musculus1Unknown0No
APPamyloid beta (A4) precursor proteinMus musculus1No0No
TYRtyrosinase (oculocutaneous albinism IA)Mus musculus1Unknown0No
CD38CD38 moleculeMus musculus1Unknown0No
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Mus musculus1Unknown0No
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2Mus musculus1Unknown0No
SYN2Synapsin IIMus musculus1No0No
CYFIP1Cytoplasmic FMR1 interacting protein 1Mus musculus1No0No
PLAURplasminogen activator, urokinase receptorMus musculus1Unknown0No
DRD1Dopamine receptor D1Mus musculus2No0No
DRD1Dopamine receptor D1Rattus norvegicus1No0No
BDNFbrain-derived neurotrophic factorMus musculus1No0No
RASD1RAS, dexamethasone induced 1Mus musculus2No0No
CNTNAP1contactin associated protein 1Mus musculus3Unknown0No
CSNK1Ecasein kinase 1, epsilonMus musculus1No0No
DRD4dopamine receptor D4Mus musculus1Unknown0No
EPS8epidermal growth factor receptor pathway substrate 8Mus musculus1No0No
GRIA2Glutamate receptor, ionotropic, AMPA 2Mus musculus1Unknown0No
GSC2goosecoid homeobox 2Mus musculus1Unknown0No
HOMER2homer homolog 2Mus musculus1No0No
HOMER3homer homolog 3Mus musculus1No0No
MBD2methyl-CpG binding domain protein 2Mus musculus2Unknown0No
NLGN2neuroligin 2Mus musculus2No0No
NLGN2neuroligin 2Rattus norvegicus1No0No
NOS2Nitric Oxide Synthase 2, inducibleMus musculus1Unknown0No
NTNG2Netrin G2Mus musculus1Unknown0No
NXF5Nuclear RNA export factor 5Mus musculus0No0No
PIK3R6phosphoinositide-3-kinase, regulatory subunit 6Mus musculus2Unknown0No
RBFOX2RNA binding protein, fox-1 homologMus musculus1Unknown0No
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1Mus musculus1No0No
SLC16A8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)Mus musculus1No0No
TRPV1transient receptor potential cation channel, subfamily V, member 1Mus musculus1No0No
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