Genetic Animal Models 192 Genetic animal models

Database updated on June 20, 2019

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Status Gene Symbol Gene Name Model Species Number of Models Syntenic Human gene score Human Syndromic Rescue Model
ADNPActivity-dependent neuroprotector homeoboxMus musculus10No1Yes
ADORA2AAdenosine A2a receptorMus musculus2Unknown3No
AHI1Abelson helper integration site 1Mus musculus3UnknownSNo
ALDH5A1Aldehyde Dehydrogenase 5 family, member A1Mus musculus4Unknown1Yes
ANK2ankyrin 2, neuronalMus musculus5No1No
ANKRD11ankyrin repeat domain 11Mus musculus3Unknown1No
APBA2amyloid beta (A4) precursor protein-binding, family A, member 2Mus musculus2Unknown3No
ARHGAP32Rho GTPase activating protein 32Mus musculus3No3Yes
ARHGEF10Rho guanine nucleotide exchange factor 10Mus musculus1No3No
ARID1BAT-rich interaction domain 1BMus musculus8No1Yes
ARXaristaless related homeoboxMus musculus5Unknown1No
ASH1LASH1 like histone lysine methyltransferaseMus musculus6No1Yes
ATP1A3Sodium potassium ATPase alpha 3 subunitMus musculus2Unknown3SYes
ATP2B2TPase, Ca++ transporting, plasma membrane 2Mus musculus1No2No
AUTS2AUTS2, activator of transcription and developmental regulatorMus musculus2No1No
AVPR1AArginine vasopressin receptor 1AMus musculus2Unknown2No
BCKDKbranched chain ketoacid dehydrogenase kinaseMus musculus3No1Yes
BCL11AB-cell CLL/lymphoma 11AMus musculus2Yes1No
CACNA1Ccalcium voltage-gated channel subunit alpha1 CMus musculus13Unknown1No
CACNA1FCalcium channel, voltage-dependent, L type, alpha 1F subunitMus musculus1No3No
CACNA1GCav3.1 T-type Ca2+ ChannelMus musculus6Unknown3No
CACNA1Hcalcium channel, voltage-dependent, T type, alpha 1H subunitMus musculus1Unknown2No
CACNA2D3calcium voltage-gated channel auxiliary subunit alpha2delta 3Mus musculus2Yes2No
CADM1cell adhesion molecule 1Mus musculus4Unknown3No
CADPS2Ca2+-dependent activator protein for secretion 2Mus musculus5Yes3No
CAMK2Acalcium/calmodulin dependent protein kinase II alphaMus musculus2No3SNo
CAPRIN1RNA granule protein 105 (Caprin 1)Mus musculus2Unknown2No
CC2D1ACoiled-coil and C2 domain containing 1AMus musculus10No2No
CD38CD38 moleculeMus musculus2Unknown3No
CDKL5cyclin-dependent kinase-like 5Mus musculus10No1Yes
CELF4CUGBP, Elav-like family member 4Mus musculus7No2No
CELF6CUGBP, Elav-like family member 6Mus musculus1No3No
CHD2chromodomain helicase DNA binding protein 2Mus musculus5No1Yes
CHD7Chromodomain Helicase DNA Binding Protein 7Mus musculus4No1Yes
CHD8chromodomain helicase DNA binding protein 8Mus musculus22No1Yes
CICcapicua transcriptional repressorMus musculus8Yes1Yes
CNTN4contactin 4Mus musculus1Unknown2No
CNTNAP2contactin associated protein-like 2Mus musculus30Unknown2SYes
CNTNAP4contactin associated protein-like 4Mus musculus7No2Yes
CSNK1Ecasein kinase 1, epsilonMus musculus1No3No
CTNNB1catenin (cadherin associated protein), beta 1Mus musculus1Yes1No
CTNND2Catenin(cadherin associated protein), delta 2Mus musculus1No2No
CUL3cullin 3Mus musculus3No1No
CYFIP1Cytoplasmic FMR1 interacting protein 1Mus musculus3No2Yes
DAGLAdiacylglycerol lipasealphaMus musculus4No3No
DEAF1DEAF1, transcription factorMus musculus9Yes2SNo
DHCR77-dehydrocholesterol reductaseMus musculus5No1No
DISC1Disrupted in schizophrenia 1Mus musculus13Unknown2No
DLG4discs, large homolog 4 (Drosophila)Mus musculus1Unknown1No
DLGAP1DLG associated protein 1Mus musculus2No2No
DMDDystrophinMus musculus6UnknownSNo
DMPKdystrophia myotonica-protein kinaseMus musculus2Unknown1No
DPP6dipeptidyl- petidase 6Mus musculus1No3No
DPYSL3dihydropyrimidinase like 3Mus musculus 1Yes3No
DRD1Dopamine receptor D1Mus musculus2No3No
DRD3Dopamine receptor D3Mus musculus3Unknown3No
DSCAMDS cell adhesion moleculeMus musculus11No1No
DVL3Dishevelled segment polarity protein 3Mus musculus5No3Yes
DYRK1Adual specificity tyrosine-Y- phosphorylation regulated kinase 1AMus musculus3No1No
EEF1A2eukaryotic translation elongation factor 1 alpha 2Mus musculus7NoSNo
EIF4EEukaryotic translation initiation factor 4EMus musculus2Yes3Yes
EN2Engrailed homeobox 2Mus musculus5Unknown3No
ERBINerbb2 interacting proteinMus musculus2No2No
ESRRBEstrogen-related receptor betaMus musculus2Unknown3No
EXT1exostosin 1Mus musculus1No3No
FEZF2FEZ family zinc finger 2Mus musculus1Unknown3No
FMR1fragile X mental retardation 1Mus musculus56Unknown1Yes
FOXG1Forkhead Box G1Mus musculus1Unknown1No
FOXP1Forkhead box P1Mus musculus7Unknown1No
FOXP2forkhead box P2Mus musculus9Unknown2No
GABRB3gamma-aminobutyric acid type A receptor beta3 subunitMus musculus22Unknown2Yes
GLRA2glycine receptor, alpha 2Mus musculus1Unknown3No
GRIA2Glutamate receptor, ionotropic, AMPA 2Mus musculus1Unknown2No
GRID2glutamate receptor, ionotropic, delta 2Mus musculus2No3No
GRIK2glutamate receptor, ionotropic, kainate 2Mus musculus4No2Yes
GRIK4Glutamate receptor, ionotropic, kainate 4Mus musculus12No3Yes
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1Mus musculus7No2Yes
GRIN2BGlutamate receptor, ionotropic, N-methyl D-aspartate 2BMus musculus10No1No
GRID1glutamate receptor, ionotropic, delta 1Mus musculus1No2No
GRIP1Glutamate receptor interacting protein 1Mus musculus3Unknown2No
GRM5glutamate receptor, metabotropic 5Mus musculus12No3No
GSTM1Glutathione S-transferase mu 1Mus musculus1Unknown3No
GTF2Igeneral transcription factor IiiMus musculus2Unknown3No
HDAC4Histone deacetylase 4Mus musculus2Unknown3SNo
HMGN1High mobility group nucleosome binding domain 1Mus musculus2Unknown2No
HOMER1homer scaffolding protein 1Mus musculus4No3No
HOXA1Homeobox A1Mus musculus3UnknownSNo
HTR1B5-hydroxytryptamine (serotonin) receptor 1BMus musculus2Unknown3No
HTR3A5-hydroxytryptamine (serotonin) receptor 3AMus musculus3Unknown3No
IL1RAPL1interleukin 1 receptor accessory protein-like 1Mus musculus2Unknown3No
IMMP2LIMP2 inner mitochondrial membrane peptidase-likeMus musculus2Unknown3No
IQSEC2IQ motif and Sec7 domain 2Mus musculus1Yes1No
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Mus musculus2Unknown2No
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1Mus musculus3Yes3No
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 2Mus musculus1Unknown2No
KCTD13potassium channel tetramerization domain containing 13Mus musculus6Yes3No
KIRREL3Kin of Irregular Chiasm-like 3Mus musculus1No2No
KMT2ALysine methyltransferase 2AMus musculus3No1No
LRFN2leucine rich repeat and fibronectin type III domain containing 2Mus musculus2No3No
LRRC4leucine rich repeat containing 4Mus musculus4No3Yes
MAGEL2MAGE like 2Mus musculus1No1No
MAOAMonoamine Oxidase AMus musculus3Unknown3No
MBD3methyl-CpG binding domain protein 3Mus musculus1Unknown3No
MCPH1microcephalin 1Mus musculus2Unknown3No
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2Mus musculus2No3No
MECP2methyl-CpG binding protein 2Mus musculus90Yes1Yes
MEF2CMyocyte Enhancer Factor 2CMus musculus9Unknown3SYes
METMET proto-oncogene, receptor tyrosine kinaseMus musculus10Unknown2No
MIR137microRNA 137Mus musculus6No2Yes
MTHFRmethylenetetrahydrofolate reductase (NAD(P)H)Mus musculus4No3Yes
NBEANeurobeachinMus musculus2Unknown1No
NEGR1neuronal growth regulator 1 Mus musculus 9No3Yes
NF1neurofibromin 1Mus musculus10Unknown1Yes
NLGN1neuroligin 1Mus musculus10Unknown2No
NLGN2neuroligin 2Mus musculus4No1No
NLGN3neuroligin 3Mus musculus43Yes1Yes
NLGN4Xneuroligin 4, X-linkedMus musculus3Unknown2No
NPAS2neuronal PAS domain protein 2Mus musculus1Unknown3No
NR3C2nuclear receptor subfamily 3, group C, member 2Mus musculus2Unknown2SNo
NRCAMNeural cell adhesion moleculeMus musculus1Unknown3No
NRP2neuropilin 2Mus musculus4Unknown3No
NRXN1neurexin 1Mus musculus2Unknown1No
NRXN2Neurexin2Mus musculus3No1No
NTNG1Netrin G1Mus musculus1Unknown3SNo
NTNG2Netrin G2Mus musculus1UnknownSNo
NUAK1NUAK family, SNF1-like kinase, 1 Mus musculus6Unknown2No
OPHN1Oligophrenin 1Mus musculus1Unknown2No
OTUD7AOTU deubiquitinase 7AMus musculus2Yes2No
OXToxytocin/neurophysin I prepropeptide [Homo sapiens (human)Mus musculus7Yes3Yes
OXTROxytocin receptorMus musculus17Unknown2Yes
PAK2p21 (RAC1) activated kinase 2Mus musculus3No2Yes
PCDH10protocadherin 10Mus musculus3Unknown3Yes
PCDH19protocadherin 19Mus musculus4No1No
PER1Period homolog 1Mus musculus1Unknown3No
PITX1paired-like homeodomain 1Mus musculus1Unknown3No
PLAURplasminogen activator, urokinase receptorMus musculus1Unknown3No
PLNPhospholambanMus musculus1Unknown3No
PRICKLE1prickle homolog 1 (Drosophila)Mus musculus5No2No
PRICKLE2prickle homolog 2 (Drosophila)Mus musculus2No2No
PRKCBProtein Kinase C, betaMus musculus1Unknown2No
PRKDCProtein kinase, DNA activated, catalytic peptideMus musculus2No3Yes
PTCHD1Patched domain containing 1Mus musculus7No1Yes
PTENphosphatase and tensin homologMus musculus23Unknown1Yes
PTGS2prostaglandin-endoperoxide synthase 2Mus musculus1No3No
RAI1retinoic acid induced 1Mus musculus12Unknown1Yes
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4Mus musculus1Unknown3No
RBFOX1RNA binding protein, fox-1 homologMus musculus2Unknown2No
RELNReelinMus musculus9Unknown1Yes
RHEBRas homolog, mTORC1 bindingMus musculus3NoSNo
RIMS1regulating synaptic membrane exocytosis 1Mus musculus10Yes1No
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3Mus musculus1No3SNo
SCN1Asodium channel, voltage-gated, type I, alpha subunitMus musculus18Unknown1Yes
SCN2Asodium voltage-gated channel alpha subunit 2Mus musculus6Unknown1Yes
SCN8Asodium channel, voltage gated, type VIII, alpha subunitMus musculus1Unknown1No
SEMA5ASema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5AMus musculus1Unknown2No
SETD5SET domain containing 5 Mus musculus2No1No
SHANK1SH3 and multiple ankyrin repeat domains 1Mus musculus2Unknown2No
SHANK2SH3 and multiple ankyrin repeat domains 2Mus musculus22No1Yes
SHANK3SH3 and multiple ankyrin repeat domains 3Mus musculus89Unknown1Yes
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2Mus musculus8NoSYes
SLC25A12solute carrier family 25 (Mitochondrial carrier, Aralar), member 12Mus musculus4Unknown3No
SLC4A10Solute carrier 4, sodium bicarbonate transporter, member 10Mus musculus1Unknown3No
SLC6A1Solute carrier family 6 member 1Mus musculus1No1No
SLC6A3solute carrier family 6 member 3Mus musculus15No2Yes
SLC6A4solute carrier family 6 member 4Mus musculus14Unknown3Yes
SLC6A8Solute carrier family 6 member 8Mus musculus2Yes3No
SLC7A5solute carrier family 7 member 5Mus musculus2No2Yes
SLC9A6solute carrier family 9, subfamily AMus musculus3No1No
SLC9A9solute carrier family 9 member A9Mus musculus3Yes3No
SLITRK5SLIT and NTRK-like family, member 5Mus musculus2No2No
SPASTSpastinMus musculus1No1No
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2Mus musculus5Unknown2Yes
STK39Serine threonine Kinase 39 (STE20/SPS1 homolog, yeast)Mus musculus1Unknown3No
STXBP1syntaxin binding protein 1Mus musculus 6Yes1Yes
SYN2Synapsin IIMus musculus3No3Yes
SYNGAP1synaptic Ras GTPase activating protein 1aMus musculus13Unknown1No
TAOK2TAO kinase 2Mus musculus5No2Yes
TBR1T-box, brain 1Mus musculus15No1Yes
SYN1Synapsin IMus musculus1No3No
TBX1T-box1Mus musculus1UnknownSNo
TCF4transcription factor 4Mus musculus4No1Yes
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Mus musculus1Unknown3No
TOP3BTopoisomerase (DNA) 3 BetaMus musculus2No3No
TRIOTrio Rho guanine nucleotide exchange factorMus musculus2No1No
TRPC6Transient receptor potential cation channel, subfamily C, member 6Mus musculus4No2Yes
TSC1tuberous sclerosis 1Mus musculus32Unknown1Yes
TSC2tuberous sclerosis 2Mus musculus16Unknown1Yes
UBE3Aubiquitin protein ligase E3AMus musculus30Unknown1Yes
TSHZ3Teashirt zinc finger homeobox 3Mus musculus2No1No
UPF3BUPF3B, regulator of nonsense mediated mRNA decayMus musculus3No1Yes
USP7Ubiquitin specific peptidase 7Mus musculus1No2SNo
WDFY3WD repeat and FYVE domain containing 3Mus musculus4Unknown1No
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