Rescue Animal Models 170 Rescue animal models

Database updated on July 10, 2017

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Status Model Symbol Type of Model Type of Rescue Rescue Agent Model Species Number of Models
SLC6A3GeneticPharmaceuticalclozapineMus musculus1
SLC6A3GeneticPharmaceuticalHaloperidolMus musculus1
SLC6A3GeneticPharmaceuticalpregnenoloneMus musculus1
SLC6A3GeneticPharmaceuticalClonidineRattus norvegicus1
SLC6A3GeneticPharmaceuticalFluoxetineRattus norvegicus1
SLC6A3GeneticPharmaceuticalQuinpiroleRattus norvegicus1
SHANK2GeneticPharmaceutical3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide (CDPPB)Mus musculus2
SHANK2GeneticPharmaceuticalD-cycloserineMus musculus1
SHANK2GeneticPharmaceuticalClioquinoleMus musculus1
SHANK2GeneticPharmaceuticalL838417Mus musculus1
SHANK2GeneticPharmaceuticalL838417Mus musculus1
SLC6A4GeneticPharmaceuticalprucaloprideMus musculus1
GRIN1GeneticPharmaceuticalBaclofenMus musculus1
GRIN1GeneticPharmaceuticalL-838,417Mus musculus1
GRIN1GeneticPharmaceuticalRisperidoneMus musculus1
IFNGGeneticPharmaceuticalDiazepamMus musculus1
IFNGGeneticPharmaceuticalRecombinant interferon gamma proteinMus musculus1
PTENGeneticPharmaceuticalRapamycinMus musculus2
TSC2GeneticPharmaceuticalEverolimusRattus norvegicus1
TSC2GeneticPharmaceuticalrapamycinMus musculus4
TSC2GeneticPharmaceuticalrapamycinMus musculus1
MECP2GeneticPharmaceuticalCorticosteroneMus musculus2
MECP2GeneticPharmaceuticalRU486Mus musculus1
MECP2GeneticPharmaceutical7,8 DHFMus musculus1
MECP2GeneticPharmaceuticalCorticosteroneMus musculus2
MECP2GeneticPharmaceuticalRU486Mus musculus1
MECP2GeneticPharmaceuticalAmpakine (CX546)Mus musculus1
MECP2GeneticPharmaceuticalASO1 (antisense oligonucleutide 1)Mus musculus1
MECP2GeneticPharmaceuticalASO2 (antisense oligonucleutide 2)Mus musculus1
MECP2GeneticPharmaceuticalASO3 (antisense oligonucleutide 3)Mus musculus1
MECP2GeneticPharmaceuticalASO4 (antisense oligonucleutide 4)Mus musculus1
MECP2GeneticPharmaceuticalASO5 (antisense oligonucleutide 5)Mus musculus1
MECP2GeneticPharmaceutical2,2',4,4'-tetrabromodiphenyl ether 47 (BDE-47)Mus musculus1
MECP2GeneticPharmaceuticalacetyl L carnitineMus musculus1
MECP2GeneticPharmaceuticalacetyl L carnitineMus musculus1
MECP2GeneticGeneticReinstatedment of Mecp2 in somatosensory neurons onlyMus musculus1
OPRM1GeneticBiologicalOxytocinMus musculus1
OPRM1GeneticBiologicalDouble mothering - social enrichmentMus musculus1
ATP1A3GeneticPharmaceuticalLithium carbonateMus musculus1
FOLH1GeneticPharmaceuticalLow folateMus musculus1
SCN1AGeneticPharmaceuticalbenzodiazepineMus musculus1
SCN1AGeneticPharmaceuticalMethylphenidateRattus norvegicus1
SLC1A2GeneticPharmaceuticalDesloratadineMus musculus1
SLC1A2GeneticPharmaceuticalFluoxetineMus musculus2
SLC1A2GeneticPharmaceuticalMemantineMus musculus1
RELNGeneticpharmaceuticalEstradiolMus musculus1
TERTGeneticPharmaceuticalMemantineMus musculus1
NRXN1GeneticGeneticAmygdala activationRattus norvegicus1
ALDH5A1GeneticPharmaceuticalCGP 35348Mus musculus1
ALDH5A1GeneticPharmaceuticalvigabatrinMus musculus1
ADNPGeneticPharmaceuticalNAPMus musculus3
ADNPGeneticPharmaceuticalSKIPMus musculus2
BCKDKGeneticDietaryhigh protein dietMus musculus1
BCKDKGeneticDietarybranched-chain amino acid dietMus musculus1
PCDH10GeneticPharmaceuticald-cycloserine (DCS)Mus musculus1
OXTGeneticbiologicalAVPMus musculus1
OXTGeneticpharmaceuticalOxytocin receptor antagonistMus musculus1
OXTGeneticbiologicalOxytocinMus musculus1
OXTGeneticGenetic and InducedCB1 receptor antagonistMus musculus1
OXTGeneticGeneticPregnancyMus musculus1
EIF4EGeneticPharmaceutical4EGI-1Mus musculus1
TCF4GeneticGeneticHdac2 shRNAsMus musculus1
TCF4GeneticPharmaceuticalSAHA (suberoylanilide hydroxamic acid)Mus musculus1
TCF4GeneticPharmaceuticalA803476Rattus norvegicus1
TCF4GeneticPharmaceuticalUCL2077Rattus norvegicus1
PRKDCGeneticCell transplantWild -type lymphocytesMus musculus1
NLGN3GeneticGeneticNlgn3Mus musculus2
NLGN3GeneticGeneticDIO-NL3 transgene in nucleus accumbensMus musculus1
PTCHD1GeneticPharmaceuticalAmphetamineMus musculus1
PTCHD1GeneticPharmaceutical1-ethyl-benzimidazolinone (1 - EBIO)Mus musculus1
GRIK2GeneticPharmaceuticalFluoxetineMus musculus1
GRIK4GeneticPharmaceuticalFlouxetineMus musculus1
GRIK4GeneticPharmaceuticalTianeptineMus musculus1
DVL1GeneticPharmaceuticalCHIR99021Mus musculus1
DVL3GeneticPharmaceuticalCHIR99021Mus musculus1
DVL1GeneticPharmaceuticalCHIR99021Mus musculus1
DVL1GeneticPharmaceuticalCHIR99021Mus musculus1
DVL3GeneticPharmaceuticalCHIR99021Mus musculus1
ARHGAP32GeneticPharmaceuticalClonazepamMus Musculus1
ARHGAP33GeneticGeneticOne Cdc42 copy knocked outMus musculus2
ARHGAP33GeneticGeneticRho deleted Noma-gap proteinMus musculus1
ARHGAP33GeneticGeneticWild type Noma-gap proteinMus musculus1
TSC1GeneticPharmaceuticalrapamycinMus musculus2
TSC1GeneticPharmaceuticalrapamycinMus musculus1
TSC1GeneticPharmaceuticalrapamycinMus musculus3
TSC1GeneticPharmaceuticalrapamycinMus musculus1
NF1GeneticPharmaceuticalIPA3Mus musculus1
NF1GeneticGeneticDeletion of PAK1Mus musculus1
PAX6GeneticPharmaceuticalClozapineRattus norvegicus1
EIF4EBP2GeneticPharmaceutical4EGIMus musculus1
EIF4EBP2GeneticPharmaceuticalshRNAs (TRCN0000032022 and TRCN0000032020)Mus musculus1
EIF4EBP2GeneticPharmaceuticalshRNAs (TRCN0000180497 and TRCN0000184441)Mus musculus1
GABRB3GeneticPharmaceuticalBaclofenMus musculus1
GABRB3GeneticPharmaceuticalCarbamazepineMus musculus1
GABRB3GeneticPharmaceuticalCGP 35348Mus musculus1
GABRB3GeneticPharmaceuticalClonazepamMus musculus1
GABRB3GeneticPharmaceuticalethosuximideMus musculus1
GABRB3GeneticPharmaceuticalTHIP (gaboxadol)Mus musculus1
GABRB3GeneticPharmaceuticalvalproic acid (VPA)Mus musculus1
Slc30a3RESCUE-PharmaceuticalPharmaceuticalMinocyclineMus musculus1
FMR1GeneticPharmaceuticalLithiumMus musculus2
FMR1GeneticPharmaceuticalMPEPMus musculus1
FMR1GeneticGeneticinactivation of one allele of App geneMus musculus1
FMR1GeneticPharmaceuticalminocyclineMus musculus1
FMR1GeneticGeneticinactivation of S6K1 geneMus musculus1
FMR1GeneticGeneticinactivation of one copy of S6K1Mus musculus1
FMR1GeneticPharmaceutical5HT 2B-R agonist BW723C86 (5mg/kg) and 5HT 2A-R-Antagonist MDL11939 (1mg/kg)Mus musculus2
FMR1GeneticPharmaceutical5HT 2B-R agonist BW723C86 (0.05mg/kg) and 5HT 2A-R-Antagonist MDL11939 (0.01mg/kg)The D1- R agonist SKF81297 (0.05mg/kg) and D2-R antagonist Sulpiride (0.25mg/kg)Mus musculus1
FMR1GeneticPharmaceuticalD1- R agonist SKF81297 (5mg/kg) and D2-R antagonist Sulpiride (25mg/kg)Mus musculus2
FMR1GeneticPharmaceuticalBumetanideMus musculus1
FMR1GeneticPharmaceutical2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP).Mus musculus2
FMR1GeneticPharmaceuticalFRAX486Mus musculus6
FMR1GeneticPharmaceuticalminocyclineMus musculus1
ATG7GeneticPharmaceuticalRapamycinMus musculus1
BRINP1GeneticPharmaceuticalMethylphenidateMus musculus1
TBR1GeneticPharmaceuticalD-cycloserineMus musculus2
TBR1GeneticGeneticin utero electroporation of micro-RNA- Cdh8 and Ntng1Mus musculus1
TBR1GeneticGeneticClioquinoneMus musculus1
TRPC6GeneticGeneticTRPC6-WTR-sh-RNAMus musculus1
CHD7GeneticGeneticReelin gene expressionMus musculus1
CHD8GeneticGeneticstablized Ctnnb1(S37A)Mus musculus1
CHD8GeneticGenetichuman CHD8Mus musculus1
CHD8GeneticGeneticstablized Ctnnb1(S37A)Mus musculus1
UBE3AGeneticPharmaceuticalApaminMus musculus1
UBE3AGeneticPharmaceuticalTHIP (gaboxadol)Mus musculus2
UBE3AGeneticGeneticReinstatement of Ube3a in glutamatergic neuronsMus musculus1
UBE3AGeneticGeneticReinstatement of Ube3a in GABAergic neuronsMus musculus1
UBE3AMultifactorialGeneticCbln1 expressionMus musculus1
AVPGeneticPharmaceuticalClozapineRattus norvegicus2
AVPGeneticPharmaceuticalHaloperidolRattus norvegicus1
AVPGeneticPharmaceuticalPD149163Rattus norvegicus2
BAIAP2GeneticPharmaceuticalmemantineMus musculus1
BAIAP2GeneticPharmaceuticalMPEPMus musculus1
ASH1LGeneticGeneticIl-6 knockoutMus musculus1
SLC7A5GeneticPharmaceuticalBCAAMus musculus1
HDCGeneticPharmaceuticalJNJ5207852Mus musculus1
HDCPharmaceutical interventionPharmaceuticalhaloperidolMus musculus2
HDCPharmaceutical interventionPharmaceuticalhistamineMus musculus1
HDCPharmaceutical interventionPharmaceuticalhaloperidolMus musculus2
HDCPharmaceutical interventionPharmaceuticalJNJ5207852Mus musculus1
HDCPharmaceutical interventionGeneticActivity-dependent and neuronal specific activation of Gi proteinMus musculus1
HDCPharmaceutical interventionPharmaceuticalJNJ5207852Mus musculus1
CICGeneticPharmaceuticalAmphetamineMus musculus2
SLC33A1GeneticGeneticSuppression of the human SLC33A1 human transgeneMus musculus1
CNTNAP2GeneticPharmaceuticalRisperidoneMus musculus1
CNTNAP2GeneticPharmaceuticalArginine VasopressinMus musculus4
CNTNAP2GeneticGeneticDREADD-Oxytocin neuronsMus musculus1
CNTNAP2GeneticPharmaceuticalFenobamMus musculus1
CNTNAP2GeneticPharmaceuticalFlumazenilMus musculus1
CNTNAP2GeneticPharmaceuticalFluoxetineMus musculus1
CNTNAP2GeneticPharmaceuticalMelanocortin 4 receptor agonistMus musculus2
CNTNAP2GeneticPharmaceuticalOxytocinMus musculus4
CNTNAP4GeneticPharmaceuticalHaloperidolMus musculus1
CNTNAP4GeneticPharmaceuticalIndipnolMus musculus1
CNTNAP4GeneticPharmaceuticalIndipnolMus musculus1
OXTRGeneticPharmaceuticalVasopressinMus musculus1
OXTRGeneticPharmaceuticalOxytocinMus musculus1
SHANK3GeneticPharmaceuticalIGF-1Mus musculus2
SHANK3GeneticPharmaceuticalpeptide derivative of IGF-1Mus musculus1
SHANK3GeneticPharmaceuticalTG003, CLK2 inhibitorMus musculus1
SHANK3GeneticBiologicalconstititutively active Rac1Mus musculus1
SHANK3GeneticPharmaceuticalp-cofilin peptideMus musculus3
SHANK3GeneticPharmaceuticalTG003, CLK2 inhibitorMus musculus1
SHANK3GeneticGeneticReversible Shank3 knockinMus musculus1
SHANK3GeneticGeneticMus musculus1
SHANK3GeneticGeneticTamoxifen for transgene inductionMus musculus2
SHANK3GeneticPharmaceuticalCDPBMus musculus2
SHANK3GeneticPharmaceuticalMPEPMus musculus1
SHANK3GeneticPharmaceuticalOxytocinRattus norvegicus1
SHANK3GeneticPharmaceuticalOxytocinRattus norvegicus1
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