Human Gene Module / Chromosome 5 / APC

APCadenomatosis polyposis coli

Score
5
Hypothesized Criteria 5.1
Autism Reports / Total Reports
2 / 9
Rare Variants / Common Variants
1 / 1
Aliases
APC, GS,  DP2,  DP3,  FAP,  FPC,  DP2.5
Associated Syndromes
-
Genetic Category
Rare Single Gene Mutation, Genetic Association, Functional
Chromosome Band
5q22.2
Associated Disorders
adenomatous polyposis coli
Relevance to Autism

Rare mutation (Barber et al., 1994) and genetic association (Zhou et al., 2007) of the APC gene has been identified with autism.

Molecular Function

The encoded protein is a tumor suppressor.

Reports related to APC (9 Reports)
# Type Title Author, Year Autism Report Associated Disorders
1 Recent Recommendation Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus. Clment G , et al. (2006) No -
2 Positive Association Association of adenomatous polyposis coli (APC) gene polymorphisms with autism spectrum disorder (ASD). Zhou XL , et al. (2007) Yes -
3 Recent Recommendation A two-step model for colon adenoma initiation and progression caused by APC loss. Phelps RA , et al. (2009) No -
4 Recent Recommendation Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. Kawasaki Y , et al. (2009) No -
5 Recent Recommendation The postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic syn... Rosenberg MM , et al. (2010) No -
6 Recent recommendation Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mohn JL , et al. (2014) No -
7 Recent recommendation APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly. Preitner N , et al. (2014) No -
8 Primary Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion. Barber JC , et al. (1994) Yes adenomatous polyposis coli
9 Highly Cited Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Morin PJ , et al. (1997) No -
Rare Variants   (1)
Status Allele Change Residue Change Variant Type Inheritance Pattern Parental Transmission Family Type Author, Year
- - copy_number_loss De novo - Simplex Barber JC , et al. (1994)
Common Variants   (1)
Status Allele Change Residue Change Variant Type Inheritance Pattern Paternal Transmission Family Type Author, Year
c.*86C>A - 3_prime_UTR_variant - - - Zhou XL , et al. (2007)
CNVs associated with APC(3 CNVs)
10q25.2-qter 1 Duplication 1  /  1
12q24.13 6 Deletion 13  /  20
3q13.13 8 Deletion-Duplication 14  /  42
Interaction Table
Interactor Symbol Interactor Name Interactor Organism Interactor Type Entrez ID Uniprot ID
11-Sep septin 11 Mouse RNA Binding 52398 Q8C1B7
4932438A13Rik RIKEN cDNA 4932438A13 gene Mouse RNA Binding 229227 A2AAE1
6-Mar membrane-associated ring finger (C3HC4) 6 Mouse RNA Binding 223455 Q6ZQ89
Abhd17c abhydrolase domain containing 17C Mouse RNA Binding 70178 Q8VCV1
Abi2 abl-interactor 2 Mouse RNA Binding 329165 P62484
ACADVL acyl-CoA dehydrogenase, very long chain Human Protein Binding 37 P49748
Acly ATP citrate lyase Mouse RNA Binding 104112 Q91V92
Actb actin, beta Mouse RNA Binding 11461 P60710
Actr1a ARP1 actin-related protein 1A, centractin alpha Mouse RNA Binding 54130 P61164
Actr1b ARP1 actin-related protein 1B, centractin beta Mouse RNA Binding 226977 Q8R5C5
Aff4 AF4/FMR2 family, member 4 Mouse RNA Binding 93736 Q9ESC8
AGFG1 ArfGAP with FG repeats 1 Human Protein Binding 3267 P52594
Akap11 A kinase (PRKA) anchor protein 11 Mouse RNA Binding 219181 E9Q777
Ank3 ankyrin 3, epithelial Mouse RNA Binding 11735 Q4U260
Ankrd12 Mouse RNA Binding Q6P211
ANKRD17 ankyrin repeat domain 17 Human Protein Binding 26057 O75179
Anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A Mouse RNA Binding 11737 O35381
Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E Mouse RNA Binding 66471 P97822
ANXA7 annexin A7 Human Protein Binding 310 P20073
AP2M1 adaptor-related protein complex 2, mu 1 subunit Human Protein Binding 1173 Q96CW1
Araf v-raf murine sarcoma 3611 viral oncogene homolog Mouse RNA Binding 11836 P04627
Arhgap11a Rho GTPase activating protein 11A Mouse RNA Binding 228482 Q80Y19
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 Human Protein Binding 50649 Q9NR80
Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 Mouse RNA Binding 211914 Q7SIG6
Atad1 ATPase family, AAA domain containing 1 Mouse RNA Binding 67979 Q9D5T0
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) Mouse RNA Binding 228033 P56384
Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 Mouse RNA Binding 70495 Q9CYN9
Atxn7l3b ataxin 7-like 3B Mouse RNA Binding 382423 Q3UD01
AXIN1 axin 1 Human Protein Binding 8312 O15169
AXIN2 axin 2 Human Protein Binding 8313 Q9Y2T1
Azin1 antizyme inhibitor 1 Mouse RNA Binding 54375 O35484
Basp1 brain abundant, membrane attached signal protein 1 Mouse RNA Binding 70350 Q91XV3
Brwd1 bromodomain and WD repeat domain containing 1 Mouse RNA Binding 93871 Q921C3
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) Human Protein Modification 699 O43683
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) Human Protein Modification 701 O60566
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) Human Protein Binding 9184 O43684
C4A complement component 4A (Rodgers blood group) Human Protein Binding 720 P0C0L4
Cadm1 cell adhesion molecule 1 Mouse RNA Binding 54725 Q8R5M8
Cadm4 cell adhesion molecule 4 Mouse RNA Binding 260299 Q8R464
Calr calreticulin Mouse RNA Binding 12317 P14211
CCDC6 coiled-coil domain containing 6 Human Protein Binding 8030 Q05CP8
Ccnd2 cyclin D2 Mouse RNA Binding 12444 P30280
Ccnj cyclin J Mouse RNA Binding 240665 Q3TZI6
Cd24a CD24a antigen Mouse RNA Binding 12484 P24807
Cdc42 cell division cycle 42 Mouse RNA Binding 12540 P60766
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) Mouse RNA Binding 12569 P61809
Cdkn1b cyclin-dependent kinase inhibitor 1B Mouse RNA Binding 12576 P46414
Celf3 CUGBP, Elav-like family member 3 Mouse RNA Binding 78784 Q8CIN6
Celf4 CUGBP, Elav-like family member 4 Mouse RNA Binding 108013 Q7TSY6
CGNL1 cingulin-like 1 Human Protein Binding 84952 Q0VF96
Chtop chromatin target of PRMT1 Mouse RNA Binding 66511 Q9CY57
Cirbp cold inducible RNA binding protein Mouse RNA Binding 12696 P60824
Cltc clathrin, heavy polypeptide (Hc) Mouse RNA Binding 67300 Q68FD5
Cnr1 cannabinoid receptor 1 (brain) Mouse RNA Binding 12801 P47746
COG4 component of oligomeric golgi complex 4 Human Protein Binding 25839 Q9H9E3
COG5 component of oligomeric golgi complex 5 Human Protein Binding 10466 Q9UP83
Cpe carboxypeptidase E Mouse RNA Binding 12876 Q00493
Crebzf CREB/ATF bZIP transcription factor Mouse RNA Binding 233490 Q91ZR3
Csde1 cold shock domain containing E1, RNA binding Mouse RNA Binding 229663 Q91W50
CSNK1A1 casein kinase 1, alpha 1 Human Protein Modification 1452 P48729
CSNK1E casein kinase 1, epsilon Human Protein Binding 1454 P49674
CSNK2A1 casein kinase 2, alpha 1 polypeptide Human Protein Modification 1457 P68400
CSNK2B casein kinase 2, beta polypeptide Human Protein Modification 1460 P67870
Cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3 Mouse RNA Binding 228410 Q99LI7
CTBP1 C-terminal binding protein 1 Human Protein Binding 1487 Q13363
Ctdspl2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 Mouse RNA Binding 329506 Q8BG15
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa Human Protein Binding 1495 P35221
CTNNA3 catenin (cadherin-associated protein), alpha 3 Human Protein Binding 29119 A8K141
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa Human Protein Binding 1499 Q9WU82
CTNNBIP1 Beta-catenin-interacting protein 1 Human Protein Binding 56998 Q9NSA3
CTNND2 catenin (cadherin associated protein), delta 2 Mouse Protein Binding 18163 O35927
Cxadr coxsackie virus and adenovirus receptor Mouse RNA Binding 13052 P97792
Cxcr4 chemokine (C-X-C motif) receptor 4 Mouse RNA Binding 12767 P70658
Cyp51 cytochrome P450, family 51 Mouse RNA Binding 13121 Q8K0C4
Dcx doublecortin Mouse RNA Binding 13193 O88809
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 Mouse RNA Binding 67040 Q501J6
Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 Mouse RNA Binding 13209 P54823
Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 Mouse RNA Binding 13211 O70133
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 Rat Protein Binding 65040 P97836
Dpysl2 dihydropyrimidinase-like 2 Mouse RNA Binding 12934 O08553
DST dystonin Human Protein Binding 667 Q03001
Dtx3 deltex 3 homolog (Drosophila) Mouse RNA Binding 80904 Q80V91
Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 Mouse RNA Binding 234663 Q6PDL0
Dynll2 dynein light chain LC8-type 2 Mouse RNA Binding 68097 Q9D0M5
Eif4h eukaryotic translation initiation factor 4H Mouse RNA Binding 22384 Q9WUK2
Elavl2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) Mouse RNA Binding 15569 Q60899
Elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) Mouse RNA Binding 15571 Q60900
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) Mouse RNA Binding 15572 Q61701
Enc1 ectodermal-neural cortex 1 Mouse RNA Binding 13803 O35709
EPAS1 endothelial PAS domain protein 1 Human Protein Binding 2034 Q99814
Epha4 Eph receptor A4 Mouse RNA Binding 13838 Q03137
ERBB2IP erbb2 interacting protein Human Protein Binding 55914 Q96RT1
EXPH5 exophilin 5 Human Protein Binding 23086 Q8NEV8
Fabp7 fatty acid binding protein 7, brain Mouse RNA Binding 12140 P51880
Fam168b family with sequence similarity 168, member B Mouse RNA Binding 214469 G3UWF0
Fam171a2 family with sequence similarity 171, member A2 Mouse RNA Binding 217219 A2A699
FBXO30 F-box protein 30 Human Protein Binding 84085 Q8TB52
FHOD1 formin homology 2 domain containing 1 Human Protein Binding 29109 Q9Y613
Fjx1 four jointed box 1 (Drosophila) Mouse RNA Binding 14221 Q8BQB4
Fnbp1l formin binding protein 1-like Mouse RNA Binding 214459 Q8K012
Foxg1 forkhead box G1 Mouse RNA Binding 15228 Q60987
Fubp1 far upstream element (FUSE) binding protein 1 Mouse RNA Binding 51886 Q91WJ8
G2e3 G2/M-phase specific E3 ubiquitin ligase Mouse RNA Binding 217558 Q5RJY2
Gdi1 Rho GDP dissociation inhibitor (GDI) alpha Mouse RNA Binding 192662 Q99PT1
GIGYF2 GRB10 interacting GYF protein 2 Human Protein Binding 26058 Q6Y7W6
Gpc2 "<span title=""The name recommended by the UniProt consortium for this chain/part."" class=""tooltipped RECOMMENDED""><a href=""#PRO_0000333842"" onclick=""uniprot.entryViews.openSectionForInternalLink('PRO_0000333842');"">Secreted glypican-2</a>" Mouse RNA Binding 71951 Q8BKV1
Gpm6a glycoprotein m6a Mouse RNA Binding 234267 P35802
Gpm6b glycoprotein m6b Mouse RNA Binding 14758 P35803
Grb10 growth factor receptor bound protein 10 Mouse RNA Binding 14783 Q60760
GSK3B glycogen synthase kinase 3 beta Human Protein Binding 2932 P49841
H1f0 "<span title=""The name recommended by the UniProt consortium for this chain/part."" class=""tooltipped RECOMMENDED""><a href=""#PRO_0000423208"" onclick=""uniprot.entryViews.openSectionForInternalLink('PRO_0000423208');"">Histone H1.0, N-terminally processed</a>" Mouse RNA Binding 14958 P10922
H3f3b H3 histone, family 3B Mouse RNA Binding 15081 P84244
Hba-a1 Mouse RNA Binding P01942
Hba-a2 hemoglobin alpha, adult chain 1 Mouse RNA Binding 15122 Q91VB8
Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex Mouse RNA Binding 15126 P06467
Hbb-y hemoglobin Y, beta-like embryonic chain Mouse RNA Binding 15135 P02104
Hdac2 Histone deacetylase 2 Mouse RNA Binding 15182 P70288
HGS hepatocyte growth factor-regulated tyrosine kinase substrate Human Protein Binding 9146 O14964
Hipk1 homeodomain interacting protein kinase 1 Mouse RNA Binding 15257 O88904
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Mouse RNA Binding 15357 Q01237
Hn1 "<span title=""The name recommended by the UniProt consortium for this chain/part."" class=""tooltipped RECOMMENDED""><a href=""#PRO_0000424488"" onclick=""uniprot.entryViews.openSectionForInternalLink('PRO_0000424488');"">Hematological and neurological expressed 1 protein, N-terminally processed</a Mouse RNA Binding 15374 P97825
Hnrnpa0 Heterogeneous nuclear ribonucleoprotein A0 Mouse RNA Binding 77134 Q9CX86
Hnrnpd heterogeneous nuclear ribonucleoprotein D Mouse RNA Binding 11991 Q60668
Hnrnpl heterogeneous nuclear ribonucleoprotein L Mouse RNA Binding 15388 Q8R081
HNRNPM heterogeneous nuclear ribonucleoprotein M Human Protein Binding 4670 P52272
Hnrnpul2 heterogeneous nuclear ribonucleoprotein U-like 2 Mouse RNA Binding 68693 Q00PI9
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 Mouse RNA Binding 15519 P07901
Hspa4 Mouse RNA Binding Q61316
HSPH1 heat shock 105kDa/110kDa protein 1 Human Protein Binding 10808 Q92598
Id4 inhibitor of DNA binding 4 Mouse RNA Binding 15904 P41139
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble Mouse RNA Binding 15926 O88844
Igfbpl1 insulin-like growth factor binding protein-like 1 Mouse RNA Binding 75426 Q80W15
Impad1 inositol monophosphatase domain containing 1 Mouse RNA Binding 242291 Q80V26
ING5 inhibitor of growth family, member 5 Human Protein Binding 84289 Q8WYH8
IQGAP1 IQ motif containing GTPase activating protein 1 Human Protein Binding 8826 P46940
Ireb2 iron responsive element binding protein 2 Mouse RNA Binding 64602 Q811J3
Irf2bp2 interferon regulatory factor 2 binding protein 2 Mouse RNA Binding 270110 E9Q1P8
Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 Mouse RNA Binding 320563 Q5RKR3
Ivns1abp influenza virus NS1A binding protein Mouse RNA Binding 117198 Q920Q8
JUP junction plakoglobin Human Protein Binding 3728 P14923
KIAA1328 KIAA1328 Human Protein Binding 57536 Q86T90
KIAA1370 KIAA1370 Human Protein Binding 56204 Q32MH5
KIAA1683 KIAA1683 Human Protein Binding 80726 Q9H0B3
Kidins220 kinase D-interacting substrate 220 Mouse RNA Binding 77480 E9Q9B7
Kif21a kinesin family member 21A Mouse RNA Binding 16564 Q9QXL2
KIF5B kinesin family member 5B Human Protein Binding 3799 P33176
Kif5c kinesin family member 5C Mouse RNA Binding 16574 P28738
KIFAP3 kinesin-associated protein 3 Human Protein Binding 22920 Q92845
Klhdc10 kelch domain containing 10 Mouse RNA Binding 76788 Q6PAR0
Klhl9 kelch-like 9 Mouse RNA Binding 242521 Q6ZPT1
Kmt2d Mouse RNA Binding Q6PDK2
KRT13 keratin 13 Human Protein Binding 3860 P13646
KRT14 keratin 14 Human Protein Binding 3861 P02533
KRT15 keratin 15 Human Protein Binding 3866 P19012
KRT17 keratin 17 Human Protein Binding 3872 Q04695
KRT19 keratin 19 Human Protein Binding 3880 P08727
KRT23 keratin 23 (histone deacetylase inducible) Human Protein Binding 25984 Q9C075
LAMA3 laminin, alpha 3 Human Protein Binding 3909 Q16787
LAMA4 laminin, alpha 4 Human Protein Binding 3910 Q16363
Laptm4a Mouse RNA Binding Q60961
Lars2 leucyl-tRNA synthetase, mitochondrial Mouse RNA Binding 102436 Q8VDC0
LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila) Human Protein Binding 9113 O95835
Leng8 leukocyte receptor cluster (LRC) member 8 Mouse RNA Binding 232798 Q8CBY3
Lime1 Lck interacting transmembrane adaptor 1 Mouse RNA Binding 72699 Q9EQR5
LIN7C lin-7 homolog C (C. elegans) Human Protein Binding 55327 Q9NUP9
LPHN1 latrophilin 1 Human Protein Binding 22859 O94910
Lrrc58 leucine rich repeat containing 58 Mouse RNA Binding 320184 Q3UGP9
Lrrn1 leucine rich repeat protein 1, neuronal Mouse RNA Binding 16979 Q61809
Luc7l3 LUC7-like 3 (S. cerevisiae) Mouse RNA Binding 67684 Q5SUF2
MACF1 microtubule-actin crosslinking factor 1 Human Protein Binding 23499 Q9UPN3
Magee1 melanoma antigen, family E, 1 Mouse RNA Binding 107528 Q6PCZ4
Map1b microtubule-associated protein 1B Mouse RNA Binding 17755 P14873
Marcks myristoylated alanine rich protein kinase C substrate Mouse RNA Binding 17118 P26645
Marcksl1 MARCKS-like 1 Mouse RNA Binding 17357 P28667
Maz MYC-associated zinc finger protein (purine-binding transcription factor) Mouse RNA Binding 17188 P56671
MBD5 methyl-CpG binding domain protein 5 Human Protein Binding 55777 Q9P267
MCM3AP minichromosome maintenance complex component 3 associated protein Human Protein Binding 8888 O60318
Mest mesoderm specific transcript Mouse RNA Binding 17294 Q07646
Mex3d mex3 homolog D (C. elegans) Mouse RNA Binding 237400 E9PUA0
Midn midnolin Mouse RNA Binding 59090 Q3TPJ7
Mlec malectin Mouse RNA Binding 109154 Q6ZQI3
Mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 Mouse RNA Binding 56772 P97783
Mllt6 Mouse RNA Binding Q8VHB4
Mn1 meningioma 1 Mouse RNA Binding 433938 D3YWE6
MUC1 mucin 1, cell surface associated Human Protein Binding 4582 P15941
MYH10 myosin, heavy chain 10, non-muscle Human Protein Binding 4628 P35580
MYH11 myosin, heavy chain 11, smooth muscle Human Protein Binding 4629 P35749
MYO6 myosin VI Human Protein Binding 4646 Q9UM54
Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit Mouse RNA Binding 78304 Q9D2U5
NAV1 neuron navigator 1 Human Protein Binding 89796 Q8NEY1
NAV2 neuron navigator 2 Human Protein Binding 89797 Q8IVL1
NAV3 neuron navigator 3 Human Protein Binding 89795 Q8IVL0
Ncan neurocan Mouse RNA Binding 13004 P55066
NCKAP5 NCK-associated protein 5 Human Protein Binding 344148 O14513
NCKAP5L NCK-associated protein 5-like Human Protein Binding 57701 Q9HCH0
Ncoa6 nuclear receptor coactivator 6 Mouse RNA Binding 56406 Q5XJV5
ND4 mitochondrially encoded NADH dehydrogenase 4 Human Protein Binding 4538 P03905
Ndn necdin Mouse RNA Binding 17984 P25233
NEB nebulin Human Protein Binding 4703 P20929
Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 Mouse RNA Binding 74513 Q8BNJ6
Neurod6 neurogenic differentiation 6 Mouse RNA Binding 11922 P48986
Nnat neuronatin Mouse RNA Binding 18111 Q61979
NOSTRIN nitric oxide synthase trafficker Human Protein Binding 115677 Q8IVI9
Npepps aminopeptidase puromycin sensitive Mouse RNA Binding 19155 Q11011
Nptn neuroplastin Mouse RNA Binding 20320 P97300
Nr2f1 nuclear receptor subfamily 2, group F, member 1 Mouse RNA Binding 13865 Q60632
Nrep neuronal regeneration related protein Mouse RNA Binding 27528 Q07475
Nsg2 neuron specific gene family member 2 Mouse RNA Binding 18197 P47759
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 Mouse RNA Binding 98415 Q80XU3
Nudt3 nudix (nucleotide diphosphate linked moiety X)-type motif 3 Mouse RNA Binding 56409 Q9JI46
Nufip2 nuclear fragile X mental retardation protein interacting protein 2 Mouse RNA Binding 68564 Q5F2E7
NUP153 nucleoporin 153kDa Human Protein Binding 9972 P49790
NUP214 nucleoporin 214kDa Human Protein Binding 8021 P35658
NUP54 nucleoporin 54kDa Human Protein Binding 53371 Q7Z3B4
NUP98 nucleoporin 98kDa Human Protein Binding 4928 P52948
NUPL1 nucleoporin like 1 Human Protein Binding 9818 Q9BVL2
NUPL2 nucleoporin like 2 Human Protein Binding 11097 O15504
Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) Mouse RNA Binding 108155 Q8CGY8
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 Mouse RNA Binding 18472 P63005
Pbrm1 Mouse RNA Binding Q8BSQ9
Pcdhg* protocadherin gamma subfamily A, 4 Mouse RNA Binding 93712 Q91XY4
Pfn2 profilin 2 Mouse RNA Binding 18645 Q9JJV2
Plekhj1 pleckstrin homology domain containing, family J member 1 Mouse RNA Binding 78670 Q9D240
PNISR PNN-interacting serine/arginine-rich protein Human Protein Binding 25957 Q8TF01
Polr2m polymerase (RNA) II (DNA directed) polypeptide M Mouse RNA Binding 28015 Q6P6I6
POM121 POM121 membrane glycoprotein Human Protein Binding 9883 Q96HA1
POM121C POM121 membrane glycoprotein C Human Protein Binding 100101267 A8CG34
Pou3f3 POU domain, class 3, transcription factor 3 Mouse RNA Binding 18993 P31361
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform Mouse RNA Binding 19046 P62141
PPP1R13B protein phosphatase 1, regulatory (inhibitor) subunit 13B Human Protein Binding 23368 Q8WUF5
PPP2CA protein phosphatase 2, catalytic subunit, alpha isoenzyme Human Protein Modification 5515 P67775
Ppp6r1 protein phosphatase 6, regulatory subunit 1 Mouse RNA Binding 243819 Q7TSI3
Prkar1a "<span title=""The name recommended by the UniProt consortium for this chain/part."" class=""tooltipped RECOMMENDED""><a href=""#PRO_0000421786"" onclick=""uniprot.entryViews.openSectionForInternalLink('PRO_0000421786');"">cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally p Mouse RNA Binding 19084 Q9DBC7
Prpf4b PRP4 pre-mRNA processing factor 4 homolog B (yeast) Mouse RNA Binding 19134 Q61136
Prrc2b proline-rich coiled-coil 2B Mouse RNA Binding 227723 Q7TPM1
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 Human Protein Binding 5707 Q99460
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) Human Protein Binding 5783 O14603
Pum1 pumilio 1 (Drosophila) Mouse RNA Binding 80912 Q80U78
Qk quaking Mouse RNA Binding 19317 Q9QYS9
R3hdm4 R3H domain containing 4 Mouse RNA Binding 109284 Q4VBF2
Rad23b RAD23b homolog (S. cerevisiae) Mouse RNA Binding 19359 P54728
RANBP9 RAN binding protein 9 Human Protein Binding 10048 Q96S59
Rbbp4 retinoblastoma binding protein 4 Mouse RNA Binding 19646 Q60972
Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 Mouse RNA Binding 93686 Q8BP71
Rbm33 RNA binding motif protein 33 Mouse RNA Binding 381626 Q9CXK9
RBM4B RNA binding motif protein 4B Human Protein Binding 83759 Q9BQ04
Rc3h2 ring finger and CCCH-type zinc finger domains 2 Mouse RNA Binding 319817 P0C090
Rcn2 reticulocalbin 2 Mouse RNA Binding 26611 Q8BP92
Rgma repulsive guidance molecule family member A Mouse RNA Binding 244058 Q6PCX7
Rgmb RGM domain family, member B Mouse RNA Binding 68799 Q7TQ33
Rimklb ribosomal modification protein rimK-like family member B Mouse RNA Binding 108653 Q80WS1
Rnd3 Rho family GTPase 3 Mouse RNA Binding 74194 P61588
Rnf145 ring finger protein 145 Mouse RNA Binding 74315 Q5SWK7
Rnf2 ring finger protein 2 Mouse RNA Binding 19821 Q9CQJ4
RP1 retinitis pigmentosa 1 (autosomal dominant) Human Protein Binding 6101 P56715
RPS27 ribosomal protein S27 Human Protein Binding 6232 P42677
Rps6kb1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 Mouse RNA Binding 72508 Q8BSK8
Rtn1 reticulon 1 Mouse RNA Binding 104001 Q8K0T0
Rtn3 reticulon 3 Mouse RNA Binding 20168 Q9ES97
Rtn4 reticulon 4 Mouse RNA Binding 68585 Q99P72
SAV1 salvador homolog 1 (Drosophila) Human Protein Binding 60485 Q9H4B6
Scd2 stearoyl-Coenzyme A desaturase 2 Mouse RNA Binding 20250 P13011
Sec23a SEC23A (S. cerevisiae) Mouse RNA Binding 20334 Q01405
SEC31A SEC31 homolog A (S. cerevisiae) Human Protein Binding 22872 O94979
Senp6 SUMO/sentrin specific peptidase 6 Mouse RNA Binding 215351 Q6P7W0
Serinc1 serine incorporator 1 Mouse RNA Binding 56442 Q9QZI8
SETDB1 SET domain, bifurcated 1 Human Protein Binding 9869 Q15047
SFN stratifin Human Protein Binding 2810 P31947
Slc38a1 solute carrier family 38, member 1 Mouse RNA Binding 105727 Q8K2P7
Slc38a2 solute carrier family 38, member 2 Mouse RNA Binding 67760 Q8CFE6
SMC3 structural maintenance of chromosomes 3 Human Protein Binding 9126 Q9UQE7
Smg7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) Mouse RNA Binding 226517 Q5RJH6
Snhg11 small nucleolar RNA host gene 11 Mouse RNA Binding 319317 Q4G0K9
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) Human Protein Binding 23020 O75643
Sox11 SRY-box containing gene 11 Mouse RNA Binding 20666 Q7M6Y2
Sox4 SRY-box containing gene 4 Mouse RNA Binding 20677 Q06831
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like Human Protein Binding 23384 Q69YQ0
SPTBN2 spectrin, beta, non-erythrocytic 2 Human Protein Binding 6712 O15020
Srsf1 serine/arginine-rich splicing factor 1 Mouse RNA Binding 110809 Q6PDM2
Srsf7 serine/arginine-rich splicing factor 7 Mouse RNA Binding 225027 Q8BL97
Srsf9 serine/arginine-rich splicing factor 9 Mouse RNA Binding 108014 Q9D0B0
Ssr3 signal sequence receptor, gamma Mouse RNA Binding 67437 Q9DCF9
SYNC Syncoilin Human Protein Binding 81493 Q9H7C4-2
Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein Mouse RNA Binding 56403 Q3TRV3
SYNE1 spectrin repeat containing, nuclear envelope 1 Human Protein Binding 23345 Q8NF91
Syt1 synaptotagmin I Mouse RNA Binding 20979 P46096
Syt11 synaptotagmin XI Mouse RNA Binding 229521 Q9R0N3
T2 Mouse RNA Binding Q06666
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa Human Protein Binding 6872 P21675
Taok1 TAO kinase 1 Mouse RNA Binding 216965 Q5F2E8
Tbc1d16 TBC1 domain family, member 16 Mouse RNA Binding 207592 Q6PFC0
Tbr1 T-box brain gene 1 Mouse RNA Binding 21375 Q64336
Tcf4 transcription factor 4 Mouse RNA Binding 21413 Q60722
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) Human Protein Binding 7020 P05549
Tle3 transducin-like enhancer of split 3, homolog of Drosophila E(spl) Mouse RNA Binding 21887 Q08122
Tle4 transducin-like enhancer of split 4, homolog of Drosophila E(spl) Mouse RNA Binding 21888 Q62441
Tmed7 transmembrane emp24 protein transport domain containing 7 Mouse RNA Binding 66676 D3YZZ5
Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 Mouse RNA Binding 230157 Q6PFE7
Tmod2 tropomodulin 2 Mouse RNA Binding 50876 Q9JKK7
Tmsb4x "<span title=""The name recommended by the UniProt consortium for this chain/part."" class=""tooltipped RECOMMENDED""><a href=""#PRO_0000034297"" onclick=""uniprot.entryViews.openSectionForInternalLink('PRO_0000034297');"">Hematopoietic system regulatory peptide</a>" Mouse RNA Binding 19241 P20065
Tmx4 thioredoxin-related transmembrane protein 4 Mouse RNA Binding 52837 Q8C0L0
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 Mouse RNA Binding 74493 Q3UES3
Tnrc6b trinucleotide repeat containing 6b Mouse RNA Binding 213988 Q8BKI2
Top2b topoisomerase (DNA) II beta Mouse RNA Binding 21974 Q64511
TPR translocated promoter region (to activated MET oncogene) Human Protein Binding 7175 P12270
TRIM21 tripartite motif-containing 21 Human Protein Binding 6737 P19474
Trp53inp1 transformation related protein 53 inducible nuclear protein 1 Mouse RNA Binding 60599 Q9QXE4
Tsc22d1 TSC22 domain family, member 1 Mouse RNA Binding 21807 P62500
Tspan3 tetraspanin 3 Mouse RNA Binding 56434 Q545L1
Ttc14 tetratricopeptide repeat domain 14 Mouse RNA Binding 67120 Q9CSP9
Tuba1a tubulin, alpha 1A Mouse RNA Binding 22142 P68369
Tubb2b tubulin, beta 2B class IIB Mouse RNA Binding 73710 Q9CWF2
Tubb5 tubulin, beta 5 class I Mouse RNA Binding 22154 P99024
Ubqln2 ubiquilin 2 Mouse RNA Binding 54609 Q9QZM0
Ubxn7 UBX domain protein 7 Mouse RNA Binding 224111 Q6P5G6
Ugcg UDP-glucose ceramide glucosyltransferase Mouse RNA Binding 22234 O88693
Vash1 vasohibin 1 Mouse RNA Binding 238328 Q8C1W1
Vcan Mouse RNA Binding Q62059
Wdr26 WD repeat domain 26 Mouse RNA Binding 226757 Q8C6G8
Wsb1 WD repeat and SOCS box-containing 1 Mouse RNA Binding 78889 O54927
XPO1 exportin 1 (CRM1 homolog, yeast) Human Protein Binding 7514 O14980
Xpr1 xenotropic and polytropic retrovirus receptor 1 Mouse RNA Binding 19775 Q9Z0U0
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide Mouse RNA Binding 22627 P62259
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide Mouse RNA Binding 22628 P61982
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Mouse RNA Binding 22631 P63101
Zfhx3 Mouse RNA Binding Q61329
ZFP106 zinc finger protein 106 homolog (mouse) Human Protein Binding 64397 Q9H2Y7
Zfp26 zinc finger protein 26 Mouse RNA Binding 22688 P10076
Zfp516 zinc finger protein 516 Mouse RNA Binding 329003 Q7TSH3
Zfp664 zinc finger protein 664 Mouse RNA Binding 269704 Q4VA44
Zic1 zinc finger protein of the cerebellum 1 Mouse RNA Binding 22771 P46684
ZNF408 zinc finger protein 408 Human Protein Binding 79797 B4DXY4
ZNF785 Zinc finger protein 785 Human Protein Binding 146540 A8K8V0-2
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